The meta search engine will also run search for some hotels and car hire facilities while AdPrecision, which specialises in contextual pay-per-click advertising, will continue to run city breaks and holidays.
The deal with TravelSupermarket will launch at the same time as a suite of new features are added to the Telegraph’s travel channel.
User navigation will be overhauled and destination facilities will be improved including the interactive map on the channel’s homepage.
AdPrecision will also serve ads across TravelSupermarket’s embedded pages.
Eamonn Lacey, product manager online for TNM, said: “This partnership will enable us to attract a wider audience to the site, which in turn will draw more attention to the smaller niche advertisers we have from working with other partners.
“Our goal is for Travelsupermarket to complement our existing travel offers and offer the consumer the widest possible choice.”
Managing director Chris Nixon said: “We are really excited about the new partnership with the Telegraph.co.uk and are delighted to be working with such a major brand in the UK.
“The partnership is also great news for our providers as we continue to supply them with quality traffic.”
TravelSupermarket currently powers travel search facilities on the Guardian’s travel section.
However the company is currently re-pitching for the business as part of a renewal process being run by the Guardian for the recently expired contract.
TravelSupermarket recently won a pitch to provide travel search facilities to the consumer portal for mobile phone and TV service provider Virgin Media.
White labelling is becoming a significant part of the business interests of meta search websites in recent months, with US player SideStep picking up a number of partnerships in recent months including search facilities for Virgin’s telecommunications rival Orange.