The appointment of Smith coincides with other changes to senior roles at the travel meta search engine, including a shift in responsibility for current flights boss Bob Atkinson, who is moving to a new position of product development manager.
Smith has also previously worked with Cheshire and Warrington Tourist Board as business development manager.
His responsibilities will include growing the flights channel alongside managing new and existing commercial relationships with airlines.
Smith said: “Travelsupermarket.com is a young and dynamic company, which is still growing at an incredible rate. I am really pleased to join the Travelsupermarket.com team and look forward to the new challenges 2008 is set to bring.”